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DeCS
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Descriptor English:
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TNF-Related Apoptosis-Inducing Ligand
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Descriptor Spanish:
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Ligando Inductor de Apoptosis Relacionado con TNF
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Descriptor Portuguese:
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Ligante Indutor de Apoptose Relacionado a TNF
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Synonyms English:
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Antigen, CD253
Apo 2 Ligand
Apo 2L Protein
Apo-2 Ligand
Apo-2L Protein
Apoptosis-Inducing Ligand, TNF-Related
CD253 Antigen
TNF Related Apoptosis Inducing Ligand
TNF Superfamily, Member 10
TRAIL Protein
Tumor Necrosis Factor Ligand Superfamily Member 10
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Tree Number:
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D12.644.276.374.750.625
D12.776.467.374.750.625
D23.529.374.750.625
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Definition English:
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A transmembrane-protein belonging to the TNF family of intercellular signaling proteins. It is a widely expressed ligand that activates APOPTOSIS by binding to TNF-RELATED APOPTOSIS-INDUCING LIGAND RECEPTORS. The membrane-bound form of the protein can be cleaved by specific CYSTEINE ENDOPEPTIDASES to form a soluble ligand form. |
History Note English:
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2007(2005)
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Allowable Qualifiers English:
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Record Number:
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52298
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Unique Identifier:
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D053221
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Occurrence in VHL:
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Similar:
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DeCS
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